Description
For the treatment and prophylaxis of angina pectoris and the treatment of variant angina.
The details on this website are a summary only, for full details please refer to the manufactures for full product details.£7.99
For the treatment and prophylaxis of angina pectoris and the treatment of variant angina.
Max 1 per customer.
The medical form below needs to be completed to purchase this product
Out of stock
For the treatment and prophylaxis of angina pectoris and the treatment of variant angina.
The details on this website are a summary only, for full details please refer to the manufactures for full product details.At the onset of an attack or prior to a precipitating event: one or two 400 microgram metered doses sprayed under the tongue. If symptoms do not resolve, this may be repeated at five minute intervals for a total of three doses. If symptoms have not resolved after a total of three doses, the patient should seek prompt medical attention.
For the prevention of exercise induced angina or in other precipitating conditions: one or two 400 microgram metered doses sprayed under the tongue immediately prior to the event.
Paediatric population:
No data are available on the use of glyceryl trinitrate in children.
Method of administration
Precautions to be taken before handling or administering the medicinal product:
The bottle should be held vertically with the valve head uppermost. If the pump is new, or has not been used for a week or more, the first actuation should be released into the air. The spray orifice should then be placed as close to the mouth as possible. The dose should be sprayed under the tongue and the mouth should be closed immediately after each dose. The spray should not be inhaled.
Patients should be instructed to familiarise themselves with the position of the spray orifice, which can be identified by the finger rest on the top of the valve, in order to facilitate orientation for administration at night. During application the patient should rest, ideally in the sitting position because of the risk of symptomatic postural hypotension. Hypotension and syncope can be a particular problem with the use of nitrates in the elderly.
Do not exceed the stated dose
Hypersensitivity to the active substance, other nitrates or to any of the excipients listed in 6.1. Acute circulatory shock including hypovolaemic shock. Cardiogenic shock, unless a sufficiently high left ventricular enddiastolic pressure is assured by intra-aortal counterpulsation or positive inotropic drugs. Severe hypotension (systolic blood pressure below 90 mm Hg). Severe anaemia, possible increased intracranial pressure (e.g. cerebral haemorrhage and head trauma), severe mitral stenosis and angina caused by hypertrophic obstructive cardiomyopathy (as it may exaggerate outflow obstruction). Concomitant administration of phosphodiesterase inhibitors used for the treatment of erectile dysfunction or pulmonary arterial hypertension, e.g, sildenafil, vardenafil, tadalafil
Any lack of effect may be an indicator of early myocardial infarction.
As with all glyceryl trinitrate preparations, use in patients with incipient glaucoma should be avoided.
Glyceryl trinitrate should be used with caution in patients in whom adequate preload is important for maintaining cardiac output (e.g. mitral stenosis, pericardial tamponade, constrictive pericarditis, orthostatic dysfunction) because administration of a vasodilator in these patients may worsen clinical status.
Glyceryl trinitrate should be used with caution in patients with cerebrovascular disease since symptoms may be precipitated by hypotension.
Glyceryl trinitrate may worsen hypoxaemia in patients with lung disease or cor pulmonale.
Arterial hypotension with bradycardia may occur in patients with myocardial infarction; this is thought to be reflexly mediated.
The use of glyceryl trinitrate could theoretically compromise myocardial blood supply in patients with left ventricular hypertrophy associated with aortic stenosis because of the detrimental effects of tachycardia and decreased aortic diastolic pressure.
Detailed haemodynamic studies in a small number of patients with valvular aortic stenosis with and without concomitant significant coronary artery disease studied in the supine position have not shown adverse effects with sublingual glyceryl trinitrate. However it seems prudent to be cautious in treating ambulant patients with the combination of angina and moderate to severe valvular aortic stenosis.
You must be 16+ to purchase this item. Always read the label and leaflet with product. Please ask for advice if in doubt before purchase.
This is a medicine; Consult your doctor or pharmacist if you have an underlying medical condition, are taking any other medication or complementary therapy, or if symptoms persist.
Seek advice before using if you are breast feeding, pregnant, planning to become pregnant, or suffer from allergies. Keep all medicines out of the reach of children.Additional ID / age checks may be required for medicines.
Warning: do not exceed the stated dose
Keep all medicines out of sight and reach of children
Store below 25°C in a dry place
Medium-chain triglycerides, ethanol (absolute), glycerol monocaprylocaprate, peppermint oil, sodium (S)-lactate, (S)-lactic acid.
Each metered dose contains 400 micrograms glyceryl trinitrate.
Excipients: contains 9.6 mg anhydrous ethanol per metered dose.
This is not a full list- Please contact the manufactures for the full up to date list of all ingrediants